INTERFERin®（专用于siRNA/miRNA转染试剂）（品牌：Polyplus）
产品特性
| 试剂名称: | INTERFERin®（专用于siRNA/miRNA转染试剂） |
| 递送的分子类型: | siRNA, miRNA (microRNA), and other oligonucleotides: pre-miRNA, mimic miRNA, antimiR… |
| 产品应用: | siRNA和其他寡核苷酸的转染 |
| 细胞类型: | 贴壁细胞和悬浮细胞 |
| 可转染的数量/次数: | 1毫升INTERFERin®足以在24孔板中进行500-1000次转染。 |
| 存储: | 5 °C ± 3°C. |
| 货号 | 试剂规格 |
|---|---|
| 101000036 | INTERFERin® 0.1 mL |
| 101000028 | INTERFERin® 1 mL |
| 101000016 | INTERFERin® 5 x 1 mL |
（产品资料及数据来源于Polyplus官网。）
产品概述
更少的siRNA，更高的沉默效率，极低的脱靶效应！
- 高效的基因沉默效应：在多种细胞中达到超过90%的基因沉默；
- 温和的转染模式：保持绝佳的细胞活率；
- 极低的脱靶效应：使用低至1 nM siRNA;
- 操作简单：优化的操作手册，兼容血清和抗生素
产品来源
Polyplus
相关论文
1、Liu, J., Cheng, Y., Zhang, X., Chen, Y., Zhu, H., Chen, K., Liu, S., Li, Z., & Cao, X. (2023). Glycosyltransferase Extl1 promotes CCR7-mediated dendritic cell migration to restrain infection and autoimmunity. Cell reports, 42(1), 111991. https://doi.org/10.1016/j.celrep.2023.111991
2、Srivastava, V., Zelmanovich, V., Shukla, V., Abergel, R., Cohen, I., Ben-Sasson, S. A., & Gross, E. (2023). Distinct designer diamines promote mitophagy, and thereby enhance healthspan in C. elegans and protect human cells against oxidative damage. Autophagy, 19(2), 474–504. https://doi.org/10.1080/15548627.2022.2078069
3、Hao, W. Y., Lou, Y., Hu, G. Y., Qian, C. Y., Liang, W. R., Zhao, J., & Wang, X. H. (2022). RNA m6A reader YTHDF1 facilitates inflammation via enhancing NLRP3 translation. Biochemical and biophysical research communications, 616, 76–81. https://doi.org/10.1016/j.bbrc.2022.05.076
4、Liu, J., Zhang, N., Zeng, J., Wang, T., Shen, Y., Ma, C., & Yang, M. (2022). N6 -methyladenosine-modified lncRNA ARHGAP5-AS1 stabilises CSDE1 and coordinates oncogenic RNA regulons in hepatocellular carcinoma. Clinical and translational medicine, 12(11), e1107. https://doi.org/10.1002/ctm2.1107
5、Przepiórska, K., Wnuk, A., Beyer, C., & Kajta, M. (2023). Amorfrutin B Protects Mouse Brain Neurons from Hypoxia/Ischemia by Inhibiting Apoptosis and Autophagy Processes Through Gene Methylation- and miRNA-Dependent Regulation. Molecular neurobiology, 60(2), 576–595. https://doi.org/10.1007/s12035-022-03087-9