Anti-EAAT1 antibody

靶标信息

Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na⁺ ions and one proton, in parallel with the counter-transport of one K⁺ ion. Mediates Cl^– flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na⁺ symport. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (By similarity).