Purified Rat Anti-Mouse Integrin β3 chain (GPIIIa, CD61) Monoclonal Antibody
Specifications
| Product Cat#: | M030-0 |
| Product type: | Primary antibody |
| Antigen: | Integrin β3 chain (GPIIIa, CD61) |
| Immunogen: | Recombinant protein |
| Species immunized: | Rat |
| Isotype: | IgG2a |
| Applications: | Immunohistochemistry; Immunoprecipitation; Western Blot |
| Reactivity: | Mouse |
| Clonality (clone number): | Monoclonal, Luc.A5 |
| Form: | Liquid |
| Buffer: | 0.5 mg purified immunoglobulin in PBS and 0.09% (w/v) sodium azide |
| Concentration: | 0.5 mg/mL |
| Purity: | Protein G affinity purified. |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: |
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Target information
The Luc.A5 antibody reacts with the murine integrin beta3 chain (GPIIIa, CD61). This glycoprotein non-covalently associates with the alphaIIb chain (CD41) to form the activation dependent platelet receptor for fibrinogen, von Willebrand factor, fibronectin, and vitronectin. Alternatively, it associates with the alphav chain (CD51) to form the integrin alphav beta3, that mediates adhesion to vitronectin, vWf, fibrinogen, and thrombospondin on platelets, monocytes, activated lymphocytes, and granulocytes.
Provider
Erpantech Laboratory