iFluor™ 594 Anti-S100 beta Antibody
Specifications
| Product Cat#: | AB-06-4852 |
| Product type: | Primary antibody |
| Antigen: | S100B |
| Immunogen: | Synthetic peptide within C-terminal human S100 beta. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Immunofluorescence (1:40-1:200) |
| Reactivity: | Human |
| Clonality: | Monoclonal, SC57-02 |
| Form: | Liquid |
| Buffer: | 1*PBS buffer (pH7.4), 30% Glycerol, 1% BSA, 0.02% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A purified. |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Conjugate: | iFluor™ 594 |
| Alternative names: | NEF antibody |
| Protein S100 B antibody | |
| Protein S100-B antibody | |
| S 100 calcium binding protein beta chain antibody | |
| S 100 protein beta chain antibody | |
| S-100 protein beta chain antibody | |
| S-100 protein subunit beta antibody | |
| S100 antibody | |
| S100 calcium binding protein beta (neural) antibody | |
| S100 calcium-binding protein B antibody | |
| S100 protein beta chain antibody | |
| S100B antibody | |
| S100B_HUMAN antibody | |
| S100beta antibody |
Target information
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Provider
Erpantech Laboratory