Antibodies for In Vivo Mouse Platelet Labeling (DyLight488)
Specifications
| Product Cat#: | X488 |
| Product type: | Primary antibody |
| Antigen: | Antibodies for In Vivo Mouse Platelet Labeling |
| Immunogen: | GPIbβ subunit of the murine platelet/megakaryocyte-specific GPIb-V-IX complex. |
| Species immunized: | Rat |
| Isotype: | IgG |
| Applications: | in vivo |
| Reactivity: | Mouse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 100 µg DyLight488-labeled immunoglobulin derivative in phosphate buffered saline containing 0.2% BSA. |
| Concentration: | 0.1 mg/mL |
| Purity: | Protein G affinity purified. |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | - |
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Target information
This antibody preparation contains a rat IgG derivative against the GPIbβ subunit of the murine platelet/megakaryocyte-specific GPIb-V-IX complex. The modified antibody has been optimized for the easy and stable in vivo labeling of circulating platelets in mice. At the recommended concentration (0.1 µg/g body weight), X488 is non-cytotoxic and does not interfere with platelet adhesion and aggregation in vivo. Also, X488 does not alter platelet adhesion on collagen/von Willebrand factor in vitro. In vivo platelet labeling has been used for intravital microscopical analysis
of platelet involvement in pathological processes, such as thrombosis.
Provider
Erpantech Laboratory