Anti-MAdCAM-1 antibody
Specifications
| Product Cat#: | AB-06-2774 |
| Product type: | Primary antibody |
| Antigen: | MAdCAM-1 |
| Immunogen: | Endothelial cells from BALB/c mouse mesenteric and peripheral lymph nodes. |
| Species immunized: | Rat |
| Isotype: | IgG2a |
| Applications: | Western Blot (1:100-1:1000); Immunoprecipitation(1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)); Immunofluorescence(1:50-1:500); Flow Cytometry (1 μg per 1 x 106 cells) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (IgG2a) |
| Form: | Liquid |
| Buffer: | TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Immunogen affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | Addressin mucosal antibody |
| hMAdCAM 1 antibody | |
| hMAdCAM-1 antibody | |
| MACAM1 antibody | |
| MADCA_HUMAN antibody | |
| MAdCAM 1 antibody | |
| MAdCAM-1 antibody | |
| Madcam1 antibody | |
| Mucosal addressin cell adhesion molecule 1 antibody |
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Target information
Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.
Provider
Erpantech Laboratory