Anti-Geminin antibody
Specifications
| Product Cat#: | AB-06-1880 |
| Product type: | Primary antibody |
| Antigen: | Geminin |
| Immunogen: | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of Geminin. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500); Immunocytochemistry (1:50); Flow Cytometry |
| Reactivity: | Human, mouse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Immunogen affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | DNA replication inhibitor antibody |
| Gem antibody | |
| GEMI_HUMAN antibody | |
| Geminin antibody | |
| Geminin DNA replication inhibitor antibody | |
| GMNN antibody | |
| OTTHUMP00000039393 antibody | |
| RP3 369A17.3 antibody |
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Target information
Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle. Inhibits the transcriptional activity of a subset of Hox proteins, enrolling them in cell proliferative control.
Provider
Erpantech Laboratory