Anti-5HT1A Receptor antibody
Specifications
| Product Cat#: | AB-06-0091 |
| Product type: | Primary antibody |
| Antigen: | 5HT1A receptor |
| Immunogen: | KLH conjugated synthetic peptide derived from human 5-HTR1A 301-400/422 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry-Paraffin (1:400-800) |
| Reactivity: | Human, Mouse, Rat, Dog, Horse, Rabbit |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 5HT1A Receptor |
| HTR1A | |
| 5-HTR1A | |
| 5 HT 1A | |
| 5 HT receptor 1A | |
| 5 HT1A | |
| 5 HT1A receptor | |
| 5 hydroxytryptamine (serotonin) receptor 1A | |
| 5 hydroxytryptamine (serotonin) receptor 1A G protein coupled | |
| 5 hydroxytryptamine receptor 1A | |
| 5-HT-1A | |
| 5-HT1A | |
| 5-hydroxytryptamine receptor 1A | |
| 5HT 1A | |
| 5HT 1A receptor | |
| 5HT receptor 1A | |
| 5HT1a | |
| 5HT1A_HUMAN | |
| ADRB2RL1 | |
| ADRBRL1 | |
| G 21 | |
| G protein coupled receptor | |
| G-21 | |
| Gpcr 18 | |
| Gpcr18 | |
| Guanine nucleotide binding regulatory protein-coupled receptor | |
| PFMCD | |
| Serotonin 1A receptor | |
| Serotonin 5HT1A receptor | |
| Serotonin receptor 1A |
Target information
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca2+ ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
Provider
Erpantech Laboratory